OVARIAN DYSGERMINOMAS IN TWO MOUNTAIN CHICKEN FROGS (LEPTODACTYLUS FALLAX)
| Autor: | April Dieter, Michael M. Garner, Scott D. Fitzgerald, Chris Tabaka, Ann E. Duncan, Matti Kiupel |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Amphibian
Ovary Dysgerminoma Fatal Outcome biology.animal Biomarkers Tumor medicine Animals Neoplasm Metastasis Ovarian Neoplasms General Veterinary biology Mountain chicken General Medicine Anatomy biology.organism_classification medicine.disease Leptodactylus medicine.anatomical_structure Octamer Transcription Factors Coelom Immunohistochemistry Animals Zoo Female Animal Science and Zoology Anura Stem cell |
| Zdroj: | Journal of Zoo and Wildlife Medicine. 38:150-153 |
| ISSN: | 1937-2825 1042-7260 |
| DOI: | 10.1638/06-015.1 |
| Popis: | This report describes the gross, histologic, and immunohistochemical features of ovarian dysgerminomas in two adult female mountain chicken frogs (Leptodactylus fallax) from the same zoological institution. One frog was found dead, and the other frog had been ill for several days with a bloated abdomen and lethargy. On necropsy, large, pale multilobulated masses replaced the left ovary in both frogs, and one frog also had numerous smaller nodules scattered throughout the coelomic viscera. Histologically, these masses were composed of sheets and cords of polyhedral discrete germ cells consistent with the diagnosis of dysgerminoma. Neoplastic cells stained positive with immunohistochemistry for Oct4, which has been reported to detect stem cells including germ cells in a variety of species, including humans. Ovarian tumors are uncommonly encountered in both reptiles and amphibians, and this report is the first report of dysgerminoma in any amphibian species. |
| Databáze: | OpenAIRE |
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