Primary diffuse large B cell lymphoma of the optic chiasm in an immunocompetent patient
| Autor: | Frances M Gómez-González, Orlando De Jesus, Román Vélez, Christian Rios-Vicil |
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| Rok vydání: | 2023 |
| Předmět: |
Male
medicine.medical_specialty Pathology Biopsy Optic chiasm Lesion 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Glioma medicine Humans medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure 030220 oncology & carcinogenesis Optic Chiasm Rituximab Methotrexate Neurosurgery Lymphoma Large B-Cell Diffuse medicine.symptom business Diffuse large B-cell lymphoma 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | BMJ case reports. 14(7) |
| ISSN: | 1757-790X |
| Popis: | Primary lymphoma of the visual pathway is rare, especially at the chiasm. Very few cases have been reported. The lesion is frequently confused with an optic–hypothalamic glioma. A 55-year-old man was found disoriented at his home by a friend and evaluated with a brain MRI which demonstrated an expansile mass located at the optic chiasm and hypothalamus level. The principal differential was a high-grade hypothalamic glioma due to the contrast enhancement. A biopsy of the chiasmal lesion was performed. Histological diagnosis of the lesion was compatible with a diffuse large B cell lymphoma. He was started on methotrexate and rituximab; however, his clinical course kept deteriorating, and he died 64 days after his presentation. All prior cases of primary lymphoma of the chiasm are reviewed. |
| Databáze: | OpenAIRE |
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