Good Practice Guidelines for the use of Statistical Regression Models in Economic Evaluations
| Autor: | Ben Kearns, Michael J. Campbell, Roberta Ara, Keith R. Abrams, Mónica Hernández Alava, Andrea Manca, Allan Wailoo |
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| Rok vydání: | 2013 |
| Předmět: |
Pharmacology
Actuarial science Health economics Cost–benefit analysis Cost effectiveness Management science Cost-Benefit Analysis Health Policy media_common.quotation_subject Public Health Environmental and Occupational Health Regression analysis Checklist Decision Support Techniques Health administration Models Economic Excellence Sample size determination Practice Guidelines as Topic Humans Regression Analysis Psychology media_common |
| Zdroj: | PharmacoEconomics. 31:643-652 |
| ISSN: | 1179-2027 1170-7690 |
| Popis: | Decision-analytic models (DAMs) used to evaluate the cost effectiveness of interventions are pivotal sources of evidence used in economic evaluations. Parameter estimates used in the DAMs are often based on the results of a regression analysis, but there is little guidance relating to these. This study had two objectives. The first was to identify the frequency of use of regression models in economic evaluations, the parameters they inform, and the amount of information reported to describe and support the analyses. The second objective was to provide guidance to improve practice in this area, based on the review. The review concentrated on a random sample of economic evaluations submitted to the UK National Institute for Health and Clinical Excellence (NICE) as part of its technology appraisal process. Based on these findings, recommendations for good practice were drafted, together with a checklist for critiquing reporting standards in this area. Based on the results of this review, statistical regression models are in widespread use in DAMs used to support economic evaluations, yet reporting of basic information, such as the sample size used and measures of uncertainty, is limited. Recommendations were formed about how reporting standards could be improved to better meet the needs of decision makers. These recommendations are summarised in a checklist, which may be used by both those conducting regression analyses and those critiquing them, to identify what should be reported when using the results of a regression analysis within a DAM. |
| Databáze: | OpenAIRE |
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