Rickettsia typhi infection in childhood
| Autor: | Emmanouil Galanakis, S Sbyrakis, Achilleas Gikas, Maria Bitsori, Efstathia Scoulica |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Adolescent Hepatosplenomegaly Murine typhus Severity of Illness Index Age Distribution Risk Factors Rickettsia typhi Epidemiology medicine Humans Sex Distribution Child Greece biology business.industry Incidence Aseptic meningitis Typhus Endemic Flea-Borne General Medicine biology.organism_classification medicine.disease Rash Anti-Bacterial Agents El Niño Child Preschool Pediatrics Perinatology and Child Health Immunology Female medicine.symptom Rickettsiales business |
| Zdroj: | Acta Paediatrica. 91:59-61 |
| ISSN: | 0803-5253 |
| Popis: | UNLABELLED Rickettsia typhi infection (murine typhus) is generally underdiagnosed in childhood, as clinical presentations are often non-specific. We present the manifestations in nine children hospitalized in the Department of Paediatrics of the University Hospital, Heraklion, Crete, over a 3-y period from 1998 to 2000. Titres > 1:400 for IgM and >1:960 for IgG and/or a fourfold increase in a second sample were considered strongly suggestive of acute infection. Children presented with prolonged fever, hepatosplenomegaly and lymphadenopathy. Five children presented with a rash. Unusual manifestations included aseptic meningitis and Kawasaki-like presentation. Laboratory findings included anaemia, leucopenia, and thrombocytopenia. Three children were treated with appropriate antibiotic regimens and all nine had a complete recovery. CONCLUSION Rickettsia typhi infection should be considered in the differential diagnosis of children residing in or returning from Southern Europe countries who present with prolonged fever, rash and lymphadenopathy. |
| Databáze: | OpenAIRE |
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