Comparison of Methods for Estimating the Plasma Inorganic Iodine and the Absolute Iodine Uptake by the Thyroid Gland
| Autor: | J. Sfontouris, S. N. Papadopoulos, G. A. Rigopoulos, D. A. Koutras |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Urinary system Clinical Biochemistry Iodide Thyroid Gland chemistry.chemical_element Urine Thyroid Function Tests Kidney Iodine Biochemistry Iodine Radioisotopes Excretion chemistry.chemical_compound Endocrinology Internal medicine Methods medicine Humans chemistry.chemical_classification Clinical Trials as Topic Creatinine Goiter Chemistry Biochemistry (medical) Thyroid Iodides Kinetics medicine.anatomical_structure Female |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 28:757-760 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-28-6-757 |
| Popis: | Three methods for estimating the plasma inorganic iodine (PII) and 2 for estimating the absolute iodine uptake (AIU) by the thyroid are compared. PII1, derived from the urinary 127I excretion over a 90 min period and the U/P ratio of radioiodine, correlates well with PII3, derived also from the same urinary 127I but the U/P ratio of creatinine instead of radioiodine. On the other hand, PIL does not correlate well with, and is significantly lower than, PII2, calculated from the 24 hr urinary 127I and the renal iodide clearance. Similarly, AIU1, calculated from PII1 and the thyroidal iodide clearance, does not correlate well with, and is systematically lower than, AIU2, calculated from the 24 hr urinary 127I and the thyroid uptake. It is concluded that, although the use of PII and AIU estimates is essential for a complete understanding of iodine kinetics, results obtained with different methods are not necessarily comparable. |
| Databáze: | OpenAIRE |
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