Cyclosporin A-Induced Gingival Overgrowth in Renal Transplant Patients

Autor: Vilber de Oliveira Bello, Jamil Awad Shibli, Mônica Afonso, Maria Regina Sposto
Rok vydání: 2003
Předmět:
Zdroj: Journal of Periodontology. 74:51-56
ISSN: 1943-3670
0022-3492
DOI: 10.1902/jop.2003.74.1.51
Popis: Background: The incidence of gingival overgrowth (GO) associated with the use of cyclosporin A (CsA) is controversial. In the present study, we determined the incidence of GO in Brazilian renal transplant patients treated with CsA and the possible associations between periodontal and pharmacological variables. Methods: The test group consisted of 20 renal transplant patients, and the control group included 20 non-transplant patients. Periodontal conditions were evaluated based on the plaque index (PI), gingival index (GI), probing depth (PD), and the rate of gingival overgrowth, together with pharmacological variables (daily CsA dose and duration of treatment). Results: A significant difference in PI (P
Databáze: OpenAIRE