Cutaneous Multiple Myeloma
| Autor: | Deepti Avasthi, Leela Krishna Vamsee Miriyala |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemotherapy-induced
Pathology medicine.medical_specialty secondary primary cancer extramedullary multiple myeloma lenalidomide Plasma cell dyscrasia Dermatology Renal amyloidosis immune system diseases hemic and lymphatic diseases medicine Multiple myeloma Lenalidomide business.industry Melanoma General Engineering Hematology medicine.disease Rash Cryoglobulinemia amyloidosis and multiple myeloma cutaneous multiple myeloma Oncology Plasmacytoma medicine.symptom business cutaneous malignant melanoma squamous cell carcinoma (scc) medicine.drug |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.17779 |
| Popis: | Multiple myeloma is a plasma cell dyscrasia characterized by abnormal bone marrow clonal plasma cells, histological confirmation of plasmacytoma, monoclonal protein in serum or urine, and evidence of end-organ damage. Organ involvement in multiple myeloma manifests as CRAB (hyperCalcemia, Renal insufficiency, Anemia, lytic Bone lesions). Cutaneous complications in multiple myeloma have been reported in many different phenotypes such as cryoglobulinemia rash, bruising, amyloid deposition, and squamous cell carcinoma. However, cutaneous metastasis of multiple myeloma is very rare with fewer than 100 cases described in the literature so far. Here, we present a case of biopsy-confirmed primary cutaneous multiple myeloma. Our case has other less common features of multiple myeloma such as renal amyloidosis and a coexisting malignant melanoma. This case report describes a unique presentation of multiple myeloma to understand the disease better. |
| Databáze: | OpenAIRE |
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