Long-term albumin infusion in decompensated cirrhosis: A review of current literature

Autor: Yu Jing Jonathan Chua, Rajesh Kumar, Yu Jun Wong, Tiing Leong Ang
Rok vydání: 2021
Předmět:
Zdroj: World Journal of Hepatology
ISSN: 1948-5182
DOI: 10.4254/wjh.v13.i4.421
Popis: Decompensated cirrhosis is characterized by chronic inflammation and severe portal hypertension leading to systemic circulatory dysfunction. Albumin infusion has been widely used in decompensated cirrhosis in patients with spontaneous bacterial peritonitis, large-volume paracentesis and hepatorenal syndrome. Emerging data suggest long-term albumin infusion has both oncotic and non-oncotic properties which may improve the clinical outcomes in decompensated cirrhosis patients. We review the current literature on both the established and potential role of albumin, and specifically address the controversies of long-term albumin infusion in decompensated cirrhosis patients.
Databáze: OpenAIRE