Therapeutic Bronchoscopy for Lung Nodules: Where Are We Now?
| Autor: | Erik, Folch, Yanglin, Guo, Michal, Senitko |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Seminars in Respiratory and Critical Care Medicine. 43:480-491 |
| ISSN: | 1098-9048 1069-3424 |
| DOI: | 10.1055/s-0042-1749368 |
| Popis: | Lobar resection has been the established standard of care for peripheral early-stage non—small cell lung cancer (NSCLC). Over the last few years, surgical lung sparing approach (sublobar resection [SLR]) has been compared with lobar resection in T1N0 NSCLC. Three nonsurgical options are available in those patients who have a prohibitive surgical risk, and those who refuse surgery: stereotactic body radiotherapy (SBRT), percutaneous ablation, and bronchoscopic ablation. Local ablation involves placement of a probe into a tumor, and subsequent application of either heat or cold energy, pulsing electrical fields, or placement of radioactive source under an image guidance to create a zone of cell death that encompasses the targeted lesion and an ablation margin. Despite being in their infancy, the bronchoscopic ablative techniques are undergoing rapid research, as they extrapolate a significant knowledge-base from the percutaneous techniques that have been in the radiologist's armamentarium since 2000. Here, we discuss selected endoscopic and percutaneous thermal and non-thermal therapies with the focus on their efficacy and safety. |
| Databáze: | OpenAIRE |
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