Use of 191Pt radiotracer for the development of enrichment procedures to detect natural levels of platinum in biological and environmental materials
| Autor: | Karel Strijckmans, F. Alt, Magali Parent, Rita Cornelis, Richard Dams |
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| Rok vydání: | 1994 |
| Předmět: |
chemistry.chemical_classification
Radioisotopes Chromatography Trace Amounts Chemistry Elution Endocrinology Diabetes and Metabolism Biochemistry (medical) Clinical Biochemistry chemistry.chemical_element General Medicine Chromatography Ion Exchange Biochemistry Inorganic Chemistry Matrix (chemical analysis) chemistry.chemical_compound Isotope Labeling Chelation Platinum Dithiocarbamate Thenoyltrifluoroacetone Nuclear chemistry Acetophenone |
| Zdroj: | Biological trace element research. |
| ISSN: | 0163-4984 |
| Popis: | The 191Pt-radiotracer is a powerful tool to develop separation and preconcentration methods for Pt. The radiotracer was produced either through 190Pt (n, gamma) 191Pt reaction on Pt enriched in 190Pt, or through 191Ir (p,n) 191Pt reaction on natural Ir, followed by Pt/Ir separation. The solvent extraction behavior of 191Pt(IV) from HCl with tributylphosphate, rubeanic acid in tributylphosphate and thenoyltrifluoroacetone in n-butylalcohol/acetophenone, followed by back-extraction with 2 mol/L NH4OH was studied. The overall recovery from a biological matrix is up to 80%. Trace amounts of 191Pt were also preconcentrated as bis-(carboxymethyl) dithiocarbamate chelates on an XAD-4 microcolumn and eluted with EtOH/1 mol/L HNO3. More than 80% is recovered in 2 mL or about 70% in 300 microL. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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