Pleural effusion caused by prostaglandin E1 preparation

Autor: H. Ishihara, Tadahiro Horiuchi, Satoshi Anayama, Yoshiki Hamada, Hiroshi Watanabe, Eiichi Sato
Rok vydání: 2003
Předmět:
Zdroj: Chest. 123(3)
ISSN: 0012-3692
Popis: We encountered a case of bilateral pleural effusion associated with prostaglandin E(1) (PGE(1)) preparation. A 75-year-old man underwent replacement surgery for an amputated hand. PGE(1) was administered at 120 micro g/d to maintain circulation after vascularization. From day 7 of administration, respiratory distress developed. On day 12, pleural effusion was observed bilaterally. By discontinuing PGE(1) and improving hypoalbuminemia, pleural effusion resolved rapidly. This is the first case report of PGE(1)-induced pleural effusion; like other drug-induced pleural effusions, discontinuing the drug resulted in rapid improvement. Although a rare complication, pleural effusion has to be suspected when a patient receiving PGE(1) experiences difficulty with breathing.
Databáze: OpenAIRE