Association between severity of cardiac dysfunction caused by ventricular pre-excitation-led dyssynchrony and cardiac function recovery after ablation in children

Autor:	Xiaomei Li, M T Li, He Jiang, Haiju Liu, Haiyan Ge, Jian Cui, Yi Zhang
Rok vydání:	2020
Předmět:	Cardiac function curve medicine.medical_specialty medicine.medical_treatment Diastole Catheter ablation 030204 cardiovascular system & hematology Ventricular Function Left 03 medical and health sciences Ventricular Dysfunction Left 0302 clinical medicine Physiology (medical) Internal medicine Medicine Humans cardiovascular diseases 030212 general & internal medicine Child Ejection fraction business.industry Proportional hazards model Hazard ratio Infant Stroke Volume Recovery of Function Ablation Confidence interval Treatment Outcome cardiovascular system Cardiology Catheter Ablation Cardiology and Cardiovascular Medicine business
Zdroj:	Journal of cardiovascular electrophysiologyREFERENCES. 31(7)
ISSN:	1540-8167
Popis:	To investigate the association between the severity of cardiac dysfunction caused by ventricular pre-excitation-led dyssynchrony and cardiac function recovery time after catheter ablation and identify predictors of cardiac function recovery after ablation.A total of 49 children underwent successful ablation (median 2.92 years). This study included 23 patients with mild cardiac dysfunction (left ventricular ejection fraction [LVEF]: 45% ≤ LVEF ≤ 55%), 15 with moderate (30% ≤ LVEF 45%), and 11 with severe (LVEF30%). The time for mean LVEF reaching 55% was 0.75, 3, and more than 12 months, respectively. The mean LVEF of children with severe cardiac dysfunction aged ≤6 years normalized within 12 months of follow-up (63.00% ± 1.41%). Mean LVEF of those aged more than 6 years did not normalize at 12 months of follow-up (38.67% ± 10.97%). LVEF recovery time was significantly different between these two age groups (median 11 months vs12 months, χPatients with higher LVDd Z scores and lower LVEF tend to have slower improvement in cardiac function after ablation. Patients with LVEF less than 30% and aged more than 6 years need more than 12 months to fully recover, and some might not even completely recover. Early catheter ablation is suggested once ventricular pre-excitation-led cardiac dysfunction is suspected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cd76d86bd1b7767e69e14794d6722a https://pubmed.ncbi.nlm.nih.gov/32343451 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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