Trypanocidal activity of chemical constituents from Lychnophora salicifolia Mart
| Autor: | Walter Vichnewski, Christiane O. Jordão, Sérgio de Albuquerque, João Luis Callegari Lopes, Glória Emília Petto de Souza |
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| Rok vydání: | 2004 |
| Předmět: |
Pharmacology
Folk medicine chemistry.chemical_classification Traditional medicine Lychnopholic acid biology Chemistry Plant Extracts Trypanosoma cruzi Flavonoid Ethyl acetate Lychnophora salicifolia Asteraceae biology.organism_classification Trypanocidal Agents Plant Leaves chemistry.chemical_compound Parasitic Sensitivity Tests Chemical constituents Animals heterocyclic compounds Chagas Disease Quercetin Lychnophora Phytotherapy |
| Zdroj: | Phytotherapy research : PTR. 18(4) |
| ISSN: | 0951-418X |
| Popis: | The ethyl acetate extract from leaves plus inflorescences of L. salicifolia showed significant trypanocidal activity against trypomastigote forms of T. cruzi, which was due to the flavonoid quercetin-7,3',4'-trimethyl ether and the sesquiterpenoid lychnopholic acid. Despite the use of some species of Lychnophora in folk medicine for pain relief, crude extracts from L. salicifolia Mart. showed no antinociceptive activity in the mouse writhing test. |
| Databáze: | OpenAIRE |
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