Iodine Monochloride/Silver Trifluoromethanesulfonate (ICl/AgOTf) as a Convenient Promoter System for O-Glycoside Synthesis
| Autor: | Göran Magnusson, Andreas Meijer, Ulf Ellervik, Teddy Ercegovic |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Mesylates
chemistry.chemical_classification Glycosylation Molecular Structure Chemistry Organic Chemistry O-glycoside synthesis Glycoside Iodides Biochemistry Combinatorial chemistry Iodine monochloride Kinetics chemistry.chemical_compound Chlorides Reagent Yield (chemistry) Organic chemistry Molecule Indicators and Reagents Silver trifluoromethanesulfonate Glycosides Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters. 3:913-915 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol015547c |
| Popis: | The novel promoter system iodine monochloride/silver trifluoromethanesulfonate (ICl/AgOTf) was evaluated with various thioglycoside donors and saccharide acceptors, and O-glycosides were obtained in 46-82% yield. Several practical advantages of the ICl/AgOTf system over known promoter systems were observed, such as convenient handling of the reagents and absence of byproducts related to N-succinimide. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|