Lymphoepithelial carcinoma of the larynx: an extremely rare tumour in a patient of Chinese descent
| Autor: | Manish Mahadeorao Bundele, Jiawei Alexander Yap, Ming Yann Lim, Julian Park Nam Goh |
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| Rok vydání: | 2023 |
| Předmět: |
Larynx
Male medicine.medical_specialty China Epstein-Barr Virus Infections Herpesvirus 4 Human Ajcc stage Lymphoepithelial carcinoma Nasoendoscopy medicine Humans Aged business.industry Head and neck cancer General Medicine medicine.disease Dysphagia Selective neck dissection Tumor recurrence medicine.anatomical_structure Carcinoma Squamous Cell Radiology medicine.symptom Neoplasm Recurrence Local business |
| Zdroj: | BMJ case reports. 14(10) |
| ISSN: | 1757-790X |
| Popis: | Lymphoepithelial carcinoma (LEC) of the larynx is an extremely rare tumour which, unlike its nasopharyngeal counterpart, has shown a propensity to affect elderly Caucasian men and is not commonly associated with Epstein-Barr virus. We present a 70-year-old Chinese man who complained of hoarseness and dysphagia. Nasoendoscopy revealed a left supraglottic tumour. Preoperative MRI (in particular Diffusion Weighted Imaging) showed the possibility of two distinct components within a tumour. The patient underwent total pharyngolaryngectomy and bilateral selective neck dissection. The final histology report confirmed the presence of a tumour with two distinct components: predominant LEC with a smaller conventional (keratinising) squamous cell carcinoma component. The patient recovered well after surgery and subsequently underwent adjuvant radiotherapy. Final staging was pT3 N2c M0 (AJCC stage IVA). Follow-up over 2 years revealed no tumour recurrence. |
| Databáze: | OpenAIRE |
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