Myocardial contrast echocardiography predicts left ventricular remodelling after acute myocardial infarction
| Autor: | Jonathan A Swinburn, Dudley J. Pennell, N G Bellenger, Roxy Senior, Michael Hickman, Paramjit Jeetley |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Perfusion index Myocardial Infarction Internal medicine medicine Humans Radiology Nuclear Medicine and imaging In patient Prospective Studies Myocardial infarction Ejection fraction Ventricular Remodeling medicine.diagnostic_test business.industry Myocardium Magnetic resonance imaging Middle Aged medicine.disease Myocardial contrast echocardiography Echocardiography Acute Disease Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American Society of Echocardiography. 17:1030-1036 |
| ISSN: | 0894-7317 |
| Popis: | Background We investigated whether the extent of residual myocardial viability demonstrated by myocardial contrast echocardiography (MCE) predicts the degree of left ventricular (LV) remodelling after acute myocardial infarction as assessed by cardiovascular magnetic resonance. Methods Accordingly, 25 patients underwent MCE 5 to 7 days after acute myocardial infarction followed by cardiovascular magnetic resonance assessment of LV end-diastolic volume, LV end-systolic volume, and LV ejection fraction. A contrast perfusion index was calculated within the infarct-related territory. Results LV end-diastolic and end-systolic volumes were significantly smaller (138 ± 38 vs 188 ± 43 mL, P = .008, and 86 ± 35 vs 119 ± 49 mL, P = .01, respectively) and LV ejection fraction was significantly higher (52 ± 5.4 vs 31.5 ± 3.2%, P > = .02) in patients showing good myocardial viability (contrast perfusion index ≤ 1.5) compared with those without viability. MCE was the only multivariate predictor of LV volumes and LV ejection fraction at 2 weeks and 6 months. Conclusions The extent of residual myocardial viability as demonstrated by MCE predicts the degree of LV remodelling after acute myocardial infarction. |
| Databáze: | OpenAIRE |
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