The recovery rate at the human terminal ileum of an orally administered non-digestive oligosaccharide (raffinose)
| Autor: | Taizo Nagura, Masashi Matsuzaka, Kazuma Danjo, Takashi Umeda, Sen Shimaya, Daisuke Chinda, Tadashi Shimoyama, Ippei Takahashi, Daisuke Saito, Shigeyuki Nakaji, Shinsaku Fukuda, Juichi Sakamoto |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Dietary Fiber
Male medicine.medical_specialty Time Factors Adolescent Administration Oral Ileum Biology Gastroenterology Young Adult chemistry.chemical_compound Raffinose Recovery rate Internal medicine medicine Terminal ileum Humans Large intestine Food science Gastrointestinal Transit chemistry.chemical_classification Test meal digestive oral and skin physiology Dietary fibre Oligosaccharide medicine.anatomical_structure Intestinal Absorption chemistry Food Science |
| Zdroj: | International Journal of Food Sciences and Nutrition. 60:344-351 |
| ISSN: | 1465-3478 0963-7486 |
| DOI: | 10.1080/09637480801990454 |
| Popis: | We clarified how raffinose, one of the non-digestive oligosaccharides, reaches the large intestine. Seven healthy male volunteers were given a test meal containing 10.0 g raffinose. A double-lumen tube was placed in the terminal ileum, and the ileal contents were aspirated through the tube. The amounts of raffinose were orally administered and collected from the terminal ileum and were compared with each other. The result was that the mean+/-standard error percentage of the amount of ingested raffinose collected in the terminal ileum was 97.1+/-2.4%. Furthermore, the average times taken for 20%, 40%, 60% and 80% of raffinose to reach the terminal ileum were 2.0+/-0.6 h, 2.6+/-0.7 h, 3.6+/-0.7 h and 4.9+/-0.7 h, respectively. In conclusion, approximately 100% of ingested raffinose was recovered in the terminal ileum in the present study. This corresponds with the present generally accepted definition of a dietary fibre. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|