Parameters predicting complications in flap surgery
| Autor: | Norbert R. Kübler, Stefan Burghardt, Christian Naujoks, Jörg Handschel, Günter Giers |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Reoperation medicine.medical_specialty Reconstructive surgery Platelet Function Tests Postoperative Hemorrhage Hemorrhagic Disorders Thrombophilia Free Tissue Flaps Surgical Flaps Pathology and Forensic Medicine Necrosis Postoperative Complications von Willebrand Factor medicine Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Prospective Studies Prospective cohort study Activated Protein C Resistance Blood coagulation test Venous Thrombosis Factor VIII Hematologic Tests business.industry Fibrinogen Thrombosis Skin Transplantation Pedicled Flap Plastic Surgery Procedures medicine.disease Surgery Venous thrombosis C-Reactive Protein Anesthesia Female Blood Coagulation Tests Oral Surgery Activated protein C resistance business Follow-Up Studies Forecasting |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 115:589-594 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2012.09.007 |
| Popis: | The aim of this prospective study was to determine laboratory parameters predicting complications and/or failure in flap surgery.Fifty-seven patients undergoing reconstructive surgery with cutaneous free and pedicled flaps were included. Blood samples were taken 2 days before surgery and 1, 3, 5, 7, and 14 days after. Parameters associated with thrombophilia, bleeding disorders, and wound healing were determined.In 45 (77%) of 57 patients no complications occurred. Bleeding (9%) and venous thrombosis of the flaps (9%) led in 18% of the cases to surgical revisions. Activated protein C resistance showed a significant (P.05) cluster in cases with venous thrombosis, whereas it was absent in all other cases. Fibrinogen, factor VIII:C, von Willebrand factor (vWF) activity, and VWF antigen were significantly (P.05) higher in patients with venous thrombosis compared with all other patients.Laboratory parameters of thrombosis and bleeding appear to be associated with complications in flap surgery. |
| Databáze: | OpenAIRE |
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