The effect of acetylsalicylic acid, caffeine, and codeine on the excretion of phenacetin metabolites

Autor: Shahidi Nt, Gault Mh, Gabe A
Rok vydání: 1972
Předmět:
Zdroj: Canadian journal of physiology and pharmacology. 50(8)
ISSN: 0008-4212
Popis: The urinary excretion of total N-acetyl-p-aminophenol and conjugates (NAPA) and total 2-hydroxyphenetidin and conjugates (2-OHP) was studied after ingestion of 2 g phenacetin alone and also in combination with acetylsalicylic acid, caffeine, and codeine (APC and C). NAPA excretion was measured in 17 patients; seven had taken the combination analgesic preparation in large amounts for 5 or more years and 11 had values for creatinine clearance of
Databáze: OpenAIRE