The effect of acetylsalicylic acid, caffeine, and codeine on the excretion of phenacetin metabolites
Autor: | Shahidi Nt, Gault Mh, Gabe A |
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Rok vydání: | 1972 |
Předmět: |
Male
Time Factors Physiology Pharmacology Tritium Excretion chemistry.chemical_compound Urinary excretion Physiology (medical) Caffeine medicine Ingestion Humans Acetaminophen Aniline Compounds Aspirin Codeine Phenacetin General Medicine Middle Aged Ethyl Ethers Kinetics chemistry Creatinine Kidney Failure Chronic Female Chromatography Thin Layer medicine.drug |
Zdroj: | Canadian journal of physiology and pharmacology. 50(8) |
ISSN: | 0008-4212 |
Popis: | The urinary excretion of total N-acetyl-p-aminophenol and conjugates (NAPA) and total 2-hydroxyphenetidin and conjugates (2-OHP) was studied after ingestion of 2 g phenacetin alone and also in combination with acetylsalicylic acid, caffeine, and codeine (APC and C). NAPA excretion was measured in 17 patients; seven had taken the combination analgesic preparation in large amounts for 5 or more years and 11 had values for creatinine clearance of |
Databáze: | OpenAIRE |
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