Coherent anti-Stokes Raman scattering microspectroscopy: an emerging technique for non-invasive optical assessment of a local bio-nano-environment
Autor: | Da-Wei Wang, Joseph T. Harrington, Anton D. Shutov, Hanlin Zhu, Delong Zhang, Vladislav V. Yakovlev |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Materials science
business.industry Non invasive Biological objects 02 engineering and technology Atomic and Molecular Physics and Optics Article symbols.namesake 020210 optoelectronics & photonics Optical imaging Nano 0202 electrical engineering electronic engineering information engineering symbols Optoelectronics Spectrogram Electrical and Electronic Engineering business Raman spectroscopy Image resolution Raman scattering |
Zdroj: | IEEE J Sel Top Quantum Electron |
Popis: | Raman spectroscopy provides a non-invasive, chemically-specific optical imaging of biological objects without relying on endogenous labels. Nonlinear Raman spectroscopy allows non-invasive imaging at much faster speed with an improved spatial resolution and axial sectioning capability. In this report we propose a novel use of nonlinear Raman spectroscopy as a sensor of local nano-environment. Time-resolved coherent anti-Stokes Raman spectrograms are found to be sensitive to small variations of local structural changes, which are not normally observed using conventional Raman spectroscopy. |
Databáze: | OpenAIRE |
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