Coherent anti-Stokes Raman scattering microspectroscopy: an emerging technique for non-invasive optical assessment of a local bio-nano-environment

Autor: Da-Wei Wang, Joseph T. Harrington, Anton D. Shutov, Hanlin Zhu, Delong Zhang, Vladislav V. Yakovlev
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: IEEE J Sel Top Quantum Electron
Popis: Raman spectroscopy provides a non-invasive, chemically-specific optical imaging of biological objects without relying on endogenous labels. Nonlinear Raman spectroscopy allows non-invasive imaging at much faster speed with an improved spatial resolution and axial sectioning capability. In this report we propose a novel use of nonlinear Raman spectroscopy as a sensor of local nano-environment. Time-resolved coherent anti-Stokes Raman spectrograms are found to be sensitive to small variations of local structural changes, which are not normally observed using conventional Raman spectroscopy.
Databáze: OpenAIRE