Validating mortality in the German Pharmacoepidemiological Research Database (GePaRD) against a mortality registry
Autor: | Oliver Riedel, Christoph Ohlmeier, Edeltraut Garbe, Ingo Langner |
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Rok vydání: | 2016 |
Předmět: |
Male
Validation study Databases Factual Epidemiology 030204 cardiovascular system & hematology German 03 medical and health sciences 0302 clinical medicine Age groups Germany Health insurance Humans Medicine Pharmacology (medical) Registries 030212 general & internal medicine Mortality Aged Probability Aged 80 and over Insurance Health business.industry Pharmacoepidemiology Middle Aged Health insurance database language.human_language language Female Medical Record Linkage business Database research Record linkage Demography |
Zdroj: | Pharmacoepidemiology and Drug Safety. 25:778-784 |
ISSN: | 1099-1557 1053-8569 |
Popis: | Purpose The study aimed at validating the status and date of death of a large electronic health insurance database against data of a mortality registry, using a probabilistic record linkage. Methods Data were obtained from one local health insurance company contributing to the German Pharmacoepidemiological Research Database (GePaRD). Furthermore, data of the Bremen Mortality Index (BreMI) containing all information from death certificates were used as reference information. Both data sources were probabilistically linked. The study sample consisted of insurants dying in 2005 or 2006. Results Of 3245 deaths in GePaRD, 83.7% were successfully linked to BreMI records. The linkage success did not differ between men and women, age groups or insurance status groups. Date of death was accurate in 97.1% of all linked deaths. Conclusions The accuracy of the status of death in GePaRD is likely to be underestimated in this study because of factors related to the record linkage procedure leading to failure of the probabilistic record linkage approach and the limited completeness of BreMI. A previous validation study comparing aggregate mortality information in GePaRD with German national statistics did not indicate an overreporting of deaths in GePaRD. Thus, a higher accuracy of the status of death in GePaRD than estimated here can be assumed. Copyright © 2016 John Wiley & Sons, Ltd. |
Databáze: | OpenAIRE |
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