Renal artery stenosis and mean platelet volume
| Autor: | Nesimi Yavuz, Turgut Karabag, Orhan Alper Güngördük, Muhammet Rasit Sayin, Mehmet Ali Çetiner, Ibrahim Ilker Oz, Mustafa Aydin |
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| Přispěvatelé: | Zonguldak Bülent Ecevit Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty complete blood count Urology Renal Artery Obstruction Kalp ve Kalp Damar Sistemi Renal artery stenosis Severity of Illness Index Severity of illness medicine Humans Mean platelet volume Retrospective Studies Original Investigation platelet renal artery stenosis mean platelet volume medicine.diagnostic_test business.industry Platelet Distribution Width Angiography Complete blood count Retrospective cohort study Middle Aged medicine.disease Disease Progression Female atherosclerosis Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Anatolian Journal of Cardiology |
| Popis: | Objective Increased mean platelet volume (MPV) has been reported in various atherosclerotic diseases. The aim of our study was to investigate the relationship between the atherosclerotic renal artery stenosis (ARAS) and various hematological parameters including MPV. Methods This study was performed with a retrospective review of the angiographic images of patients who underwent renal angiography at Bulent Ecevit University catheter laboratory between January 2004 and December 2009. The patients were trichotomized into three groups based on the presence and severity of renal artery stenosis (RAS). Group 1 included patients with a critical RAS (33 patients; 18 female (F), 15 male (M); mean age 61.6 ± 11.5 years), group 2 consisted of patients with non-critical RAS (26 patients; 15 F, 11 M; mean age 58. 1 ± 11.3 years), and group 3 was composed of patients without RAS (69 patients; 38 F, 31 M; mean age 53.5 ± 11.9 years). Demographic data, complete blood count, and biochemical parameters were compared between the groups. Results Comparison of the hematological parameters revealed that MPV and platelet distribution width were significantly higher in group 1 than in group 2 and 3 (8.96 ± 0.99 fL versus 8.35 ± 0.76 fL, 8.31 ± 0.79 fL, respectively; p=0.001; 16.53 ± 0.58% versus 16.19 ± 0.56%, 16.29 ± 0.53%, respectively; p=0.04). Conclusion MPV levels are higher in patients with ARAS. Considering both the effect of platelets on atherosclerosis and their close association with other risk factors, MPV level may be an important factor in pathogenesis of ARAS. |
| Databáze: | OpenAIRE |
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