Chemical constituents of Machaerium hirtum Vell. (Fabaceae) leaves and branches and its anti-inflammatory activity evaluation
| Autor: | Ivânia T.A. Schuquel, Ciomar Aparecida Bersani-Amado, Laura Lícia Milani de Arruda, Geanderson Bannwart, Marcos Felipe Pinatto Botelho, Silvana Maria de Oliveira Santin, Rodrigo Monteiro Fabrão, Marlene Capelin Ignoato, Armando M. Pomini |
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| Rok vydání: | 2012 |
| Předmět: |
Magnetic Resonance Spectroscopy
Proline Isovitexin Friedelin Anti-Inflammatory Agents Stigmasterol Plant Science Biology Biochemistry Analytical Chemistry Terpene chemistry.chemical_compound Mice Triterpene Botany Animals Edema Apigenin Medicinal plants Lupeol chemistry.chemical_classification Plant Extracts Organic Chemistry Fabaceae Sitosterols Triterpenes Plant Leaves chemistry Pentacyclic Triterpenes |
| Zdroj: | Natural product research. 27(17) |
| ISSN: | 1478-6427 |
| Popis: | Leaves and branches of Machaerium hirtum Vell. (Fabaceae), native to South America, were subjected to phytopharmacological investigation in order to identify its major chemical constituents and evaluate its extracts, fractions and isolated compounds in assays for anti-inflammatory activities. These were performed using mouse ear edema model, pleurisy and myeloperoxidase activity assays. Six compounds were isolated and identified as the flavanones swertisin and isovitexin, the alkaloid 4-hydroxy-N-methylproline, the triterpenes friedelin and lupeol, and the steroids sitosterol and stigmasterol. These compounds were identified by nuclear magnetic resonance of (1)H and (13)C data, in comparison with literature. |
| Databáze: | OpenAIRE |
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