Additional file 9 of Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina

Autor: F. Carlier, M. Li, L. Maroc, R. Debuchy, C. Souaid, D. Noordermeer, P. Grognet, Malagnac, F.
Rok vydání: 2021
DOI: 10.6084/m9.figshare.14559206
Popis: Additional file 9: Figure S9. Localization of histone marks on specific genomic regions in the ΔPaKmt1 and ΔPaKmt6 mutant strains. Top panel: Plots of normalized ChIP-seq signal. Bottom panel: Heatmaps divided in K-means built clusters representing the association versus non-association of the indicated histone modifications with the specific genomic regions. Coding sequences or CDS were aligned by their two ends (indicated by START and STOP) ± 1 kbp of surrounding sequence (N = 10,839; Additional file 20: Table S2); repeats were defined as TE bodies, duplications and the rDNA array ± 0.2 kbp surrounding regions (N = 1680; Additional file 21: Table S3). Histone modification levels in the heatmaps were calculated for non-overlapping 10 bp windows within the specific genomic regions and sorted by average value of each row.
Databáze: OpenAIRE