Rioprostil vs. Ranitidine in Duodenal Ulcer Healing: A Double-Blind Multicentre Trial
| Autor: | A. Lavignolle, A. Raillat, J. L. Slama, J. M. Viteau, B. Veyres, P. Lebourgeois, J. C. Audigier, J. Abgrall, H. Parlier, M. Vray, P. Dupuy, L. Le Bodic, T. Toulet, F. Prunieras, P. Rampal |
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| Rok vydání: | 1989 |
| Předmět: |
Adult
Male medicine.medical_specialty Rioprostil Ranitidine Gastroenterology law.invention Double blind Double-Blind Method Randomized controlled trial law Internal medicine Prostaglandins Synthetic Humans Multicenter Studies as Topic Medicine Randomized Controlled Trials as Topic medicine.diagnostic_test business.industry Prostaglandins E Anti-ulcer Agent Anti-Ulcer Agents Endoscopy Clinical trial Duodenal ulcer Duodenal Ulcer Female business medicine.drug |
| Zdroj: | Scandinavian Journal of Gastroenterology. 24:194-197 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.3109/00365528909091212 |
| Popis: | A total of 156 patients with endoscopically proven duodenal ulcers are randomized in a double-blind, multicentre trial comparing rioprostil, 300 micrograms b.d., with ranitidine, 150 mg b.d. With rioprostil, the cumulative healing rate by endoscopy is 73% at 4 weeks, and 87% at 6 weeks. With ranitidine it is 79% and 92%, respectively. There is no difference in the occurrence of pain after the two types of treatment, and the side effects are comparable in the two groups. These results show that rioprostil is probably as effective and safe as ranitidine in the treatment of duodenal ulcer. |
| Databáze: | OpenAIRE |
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