Prospective analysis of transvalvular systolic flow and aortic wall changes in bicuspid aortic valve insufficiency
| Autor: | Iver Petersen, Evaldas Girdauskas, Beatrix Fey, Thomas Kuntze, T. Scholle, Mina Rouman, Bernhard Theis, Kushtrim Disha |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Pulmonary and Respiratory Medicine
Aorta medicine.medical_specialty business.industry General Medicine medicine.disease Aortic wall Cardiac surgery Surgery Prospective analysis Stenosis Bicuspid aortic valve Aortic valve replacement Cardiothoracic surgery medicine.artery Internal medicine cardiovascular system medicine Cardiology Oral Presentation ddc:610 Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiothoracic Surgery |
| Popis: | Methods A total of 76 consecutive patients with BAV disease (57±10 years, 71% male) underwent aortic valve replacement (AVR) ± proximal aortic surgery from January, 2012 through April, 2013. There was a subgroup of 58 (76%) patients with BAV stenosis (Group I), whereas the remaining 18 (14%) patients had isolated BAV insufficiency (Group II). Preoperative cardiac phase-contrast cinemagnetic resonance imaging (MRI) was performed in order to detect the area of maximal flow-induced stress in the proximal aorta. Based on MRI-data, two aortic wall samples i.e., area of the maximal stress (jet-sample) and the opposite aortic wall (control-sample) were collected during surgery. Aortic wall changes were graded based on 7 histological criteria (i.e., each from 0 to 3+) and were summarized in a sum-score. Histological sum-score (0 to 21+) was calculated and compared between samples (i.e., jetvs. control-sample). |
| Databáze: | OpenAIRE |
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