Atherosclerotic carotid bifurcation phantoms with stenotic soft inclusions for ultrasound flow and vessel wall elastography imaging
| Autor: | Richard G.P. Lopata, Hongliang Li, Boris Chayer, Marie Hélène Roy Cardinal, Guy Cloutier, Marcel van den Hoven, Abigail Swillens |
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| Přispěvatelé: | Biomedical Engineering, Cardiovascular Biomechanics |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Strain elastography
Materials science duplex ultrasound Flow (psychology) 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.artery Elastic Modulus medicine Carotid bifurcation Humans Radiology Nuclear Medicine and imaging Carotid Stenosis flow loop experiments shear wave elastography Shear wave elastography Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Phantoms Imaging Ultrasound vascular phantom Plaque Atherosclerotic strain elastography Carotid Arteries phantom fabrication process 030220 oncology & carcinogenesis Elasticity Imaging Techniques carotid atherosclerotic plaque Ultrasonic sensor Elastography Internal carotid artery business Algorithms Biomedical engineering |
| Zdroj: | Physics in Medicine and Biology, 64(9):095025. Institute of Physics |
| ISSN: | 0031-9155 |
| Popis: | As the complexity of ultrasound signal processing algorithms increases, it becomes more difficult to demonstrate their added value and thus robust validation strategies are required. We propose a method of manufacturing ultrasonic vascular phantoms mimicking an atheromatous plaque in an internal carotid artery bifurcation for applications in flow imaging and elastography. During the fabrication process, a soft inclusion mimicking a stenotic lipid pool was embedded within the vascular wall. Mechanical testing measured Young's moduli of the vascular wall and soft inclusion at 342 ± 25 kPa and 17 ± 3 kPa, respectively. B-mode, color Doppler, power Doppler, shear wave elastography, and strain elastography images of the different phantoms were produced to show the validity of the fabrication process. Because of their realistic geometries and mechanical properties, those phantoms may become advantageous for fluid-structure experimental modeling and validation of new ultrasound-based imaging technologies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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