Performance of 2-Hydroxy-1-Naphthaldehyde-2-Amino Thiazole as a Highly Selective Turn-on Fluorescent Chemosensor for Al(III) Ions Detection and Biological Applications
| Autor: | Immanuel David Charles, Karthick Sivalingam Nallathambi, Summaya Banu Basha, Nandhakumar Raju, Usha Singaravelu, Hemalatha Kuzhandaivel |
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| Rok vydání: | 2021 |
| Předmět: |
Schiff base
Sociology and Political Science 010405 organic chemistry Metal ions in aqueous solution Clinical Biochemistry Naphthalenes 010402 general chemistry 01 natural sciences Biochemistry Binding constant Fluorescence Combinatorial chemistry 0104 chemical sciences Ion Turn (biochemistry) Thiazoles Clinical Psychology chemistry.chemical_compound Spectrometry Fluorescence chemistry Density functional theory Thiazole Law Spectroscopy Social Sciences (miscellaneous) |
| Zdroj: | Journal of Fluorescence. 31:1041-1053 |
| ISSN: | 1573-4994 1053-0509 |
| DOI: | 10.1007/s10895-021-02722-3 |
| Popis: | The thiazole based Schiff base 2-hydroxy-1-naphthaldehyde-2-amino thiazole (receptor1) was synthesized through a single step process and characterized by spectroscopic and analytical techniques. The cation detecting ability of the receptor1 was explored by fluorescent spectroscopic methods. The receptor1 has recognized Al3+ ions by a turn-on process over a panel of other potentially competing metal ions. The binding constant of receptor1 with Al3+ was found to be 8.27 × 103 M−1. Computational studies Density Functional Theory (DFT) and Time-dependent Density Functional Theory (TD-DFT) were performed to provide detailed information on electronic states and photophysical property of receptor1 and receptor1-Al3+ ions. MTT (3-(4,5-dimethyl thiazole-2-yl)-2,5-diphenyl tetrazolium bromide) assay and bioimaging applications were made on breast carcinoma cells in humans. |
| Databáze: | OpenAIRE |
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