Genetic Diversity and Ancestral Study for Korean Native Pigs Using 60K SNP Chip
| Autor: | Seung Hwan Lee, Hyo Dong Han, Dong Jun Kim, Eun Seok Cho, Bong Hwan Choi, Yeon Bok Jung, Dongwon Seo, Tae-Jeong Choi, Soo Hyun Lee, Yong Min Kim, Joon Ki Hong |
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| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Linkage disequilibrium Population SNP Biology Korean native pigs 01 natural sciences Article 03 medical and health sciences Korean Native lcsh:Zoology diversity study lcsh:QL1-991 education 60K Beadchip 030304 developmental biology 0303 health sciences Genetic diversity education.field_of_study lcsh:Veterinary medicine General Veterinary ancestry worldwide pigs SNP genotyping Genetic distance Genetic marker Evolutionary biology Genetic structure lcsh:SF600-1100 Animal Science and Zoology 010606 plant biology & botany |
| Zdroj: | Animals Volume 10 Issue 5 Animals, Vol 10, Iss 760, p 760 (2020) Animals : an Open Access Journal from MDPI |
| ISSN: | 2076-2615 |
| Popis: | The Korean native pig (KNP Sus scrofa coreanus) is an indigenous porcine breed in South Korea considered as a valuable but dwindling genetic resource. Studies using diverse methodologies and genetic markers suggest that this population originated from the Manchu province of Northeastern China and migrated approximately 3000 years ago into the Korean peninsula. This study aimed to verify those findings by performing diversity and ancestral analyses using the 60K single-nucleotide polymorphism (SNP) BeadChip on 891 pigs of 47 breeds worldwide. We also performed principal component analysis (PCA), ancestry analyses, phylogenetic tree analysis using SNPhylo, and linkage disequilibrium analysis. Furthermore, we generated heatmap, obtained Nei&rsquo s genetic distance and FST values, and explored the heterozygosity of commercial and native Korean pigs. The results demonstrated that KNP pigs are more closely related to European breeds than to Chinese breeds. In addition, as previous studies have suggested, our admixture analyses indicated that KNP pigs showed distinguishable genetic structure. |
| Databáze: | OpenAIRE |
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