Influence of Inoculation Site of Combined Oil-Adjuvanted Vaccine on the Antibody Response in Chickens

Autor: Yoshihiro Sakanoue, Toshinori Iwamoto, Takashi Honda, Kazuhiro Deguchi, Kazuo Matsuo, Hideo Fujikawa
Rok vydání: 1998
Předmět:
Zdroj: Journal of Veterinary Medical Science. 60:831-835
ISSN: 1347-7439
0916-7250
DOI: 10.1292/jvms.60.831
Popis: Inactivated oil-adjuvanted vaccines for ND, IB, and IC serotypes A and C (OILVAX NB2AC) have been marketed from 1993. In the outdoors, various inoculation sites have been used in chickens because to make the inoculation procedure easier. We examined whether differences would be obtained in the antibody response according to the inoculation sites; the subcutaneous inoculation into the back of the neck for OILVAX use, and the thigh, lower thigh, breast and shoulder muscle for the possible application of the inoculation outdoors. The clear order was not found in the NDV-HI titer, IBV-SN titer against Nerima or TM-86 among the inoculation sites used during the examination period. The IC serotypes A and C HI titers did vary among the inoculation sites; the subcutaneous inoculation produced the highest antibody titer, and high antibody titers were observed in the order of lower thigh muscle > or = thigh muscle > breast muscle > or = shoulder muscle inoculation.
Databáze: OpenAIRE