The response of the neuronal activity in the somatosensory cortex after high-intensity intermediate-frequency magnetic field exposure to the spinal cord in rats under anesthesia and waking states
| Autor: | Yukihisa Suzuki, Atsushi Saito, Satoshi Nakasono, Keiji Wada |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Stimulation Stimulus (physiology) Somatosensory system 03 medical and health sciences 0302 clinical medicine In vivo Evoked Potentials Somatosensory Medicine Premovement neuronal activity Animals Anesthesia Wakefulness Molecular Biology Neurons business.industry General Neuroscience High intensity Magnetic field exposure Somatosensory Cortex Spinal cord Evoked Potentials Motor Rats 030104 developmental biology medicine.anatomical_structure Magnetic Fields Spinal Cord Neurology (clinical) business 030217 neurology & neurosurgery Developmental Biology |
| Zdroj: | Brain research. 1747 |
| ISSN: | 1872-6240 |
| Popis: | Novel technologies using the intermediate-frequency magnetic field (IF-MF) in living environments are becoming popular with the advance in electricity utilization. However, the biological effects induced by the high-intensity and burst-type IF-MF exposure used in the wireless power transfer technologies for electric vehicles or medical devices, such as the magnetic stimulation techniques, are not well understood. Here, we developed an experimental platform using rats, that combined an 18 kHz, high-intensity (Max. 88 mT), Gaussian-shaped burst IF-MF exposure system with an in vivo extracellular recording system. In this paper, we aimed to report the qualitative differences in stimulus responses in the regions of the somatosensory cortex and peripheral nerve fibers that were induced by the IF-MF exposure to the rat spinal cord. We also report the modulation of the stimulus responses in the somatosensory cortex under anesthesia or waking states. Using this experimental platform, we succeeded in the detection of the motor evoked potentials or the neuronal activity in the somatosensory cortex that was induced by the IF-MF exposure to the spinal cord in rats. Compared to the state of anesthesia, the neuronal activities in the somatosensory cortex was enhanced during the waking state. On the other hand, these neuronal responses could not be confirmed by the IF-MF exposure-related coil sound only. Our experimental results indicated the basic knowledge of the biological responses and excitation mechanisms of the spinal cord stimulation by the IF-MF exposure. |
| Databáze: | OpenAIRE |
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