The technical aspects, interpretation of data, and clinical application of high-resolution esophageal manometry
| Autor: | E. R. Valitova, E. L. Nikonov, Sergey Morozov, Dmitry S. Bordin, Albert J. Bredenoord, V. O. Kaibysheva, E. D. Fedorov, A. A. Smirnov, S. G. Shapoval'yants, Vasily Isakov |
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| Přispěvatelé: | Gastroenterology and Hepatology, AGEM - Digestive immunity, AGEM - Endocrinology, metabolism and nutrition |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
business.industry
Gastroenterology High resolution computer.software_genre Interpretation (model theory) 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Medicine 030211 gastroenterology & hepatology Artificial intelligence business computer Natural language processing |
| Zdroj: | Russian Journal of Evidence-Based Gastroenterology, 7(1), 4-27. Media Sphera Publishing Group |
| ISSN: | 2305-2260 |
| Popis: | Aims ? the objective of the present article was to describe the methodology of high-resolution esophageal manometry and analysis of its results in the context of their conformity with the requirements of the modern internationally accepted guidelines. Another objective was to demonstrate the clinical significance of investigations into the motor function of the oesophagus for making the diagnosis of oesophageal disorders, their differential diagnostics, and the choice of the adequate treatment strategies in the patients presenting with these conditions. Basic premises. Pathogenesis of many oesophageal problems is associated with the disturbances of the motor function of the thoracic oesophagus and/or the lower oesophageal sphincter (LES). High-resolution esophageal manometry makes it possible to measure resting pressure at the level of the upper and lower oesophageal sphincters, to estimate the degree of their opening in response to swallowing, to evaluate the force of muscular contraction in the thoracic oesophagus, to determine the location of the upper and lower oesophageal sphincters (i.e. their distance from the nostrils) as well as the total length of the oesophagus. Moreover, highresolution manometry permits to detect the gastroesophageal hernia and determine its size, reveal spastic contractions, estimate the effectiveness of esophageal motility, and discover a barrier preventing the bolus passage at the level of sphincters. The evaluation of changes in oesophageal motility is of primary importance for differential diagnostics in the patients suffering from dysphagia and non-coronarogenic chest pain, achalasia cardiae, other organic and functional diseases of the oesopahgus as well as for taking decision as regards the necessity of endoscopic or surgical intervention for the treatment of gastroesophageal reflux diseases and achalasia cardiae. Conclusion. High-resolution esophageal manometry should be recommended for the management of the patients presenting with the clinical symptoms suggesting possible disturbances of the motor function in the thoracic oesophagus (such as dysphagia retrosternal pain, regurgitation, and belching). Of special importance is the evaluation of the motor function of the oesophagus for taking the final decision as regards the necessity of endoscopic or surgical intervention for the treatment of gastroesophageal reflux diseases and achalasia cardiae. At present, high-resolution esophageal manometry is considered to be ?the golden standard? in diagnotsics of the disturbances in the motor function of the oesophagus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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