Serological Survey following SARS-COV-2 Outbreaks at Long Term Care Facilities in Metro Vancouver, British Columbia: Implications for Outbreak Management and Infection Control Policies
| Autor: | Inna Sekirov, Michael Schwandt, Suni Boraston, Rohit Vijh, Paul N. Levett, Cher Ghafari, Muhammad Morshed, John Harding, Mark Lysyshyn, Patricia Daly, Mel Krajden, Annie Mak, Navdeep Chahil, Althea S. Hayden, Geoffrey McKee, Meghan McLennan |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Epidemiology Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serology Serology COVID-19 Serological Testing Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Environmental health Infection control Medicine Humans 030212 general & internal medicine Aged Aged 80 and over 0303 health sciences long term care British Columbia 030306 microbiology business.industry SARS-CoV-2 Public health Health Policy Brief Report Public Health Environmental and Occupational Health Outbreak COVID-19 Middle Aged Long-Term Care infection control Case definition Long-term care Infectious Diseases Cross-Sectional Studies Female Public Health clinical case definition business Infection Control Practitioners |
| Zdroj: | American Journal of Infection Control |
| ISSN: | 1527-3296 0196-6553 |
| Popis: | Highlights • Myalgias, headaches, loss of appetite and having three or more negative nasopharyngeal swabs were significantly associated with seropositivity among individuals with a negative or no previous diagnostic test. • Canadian, European and WHO's case definitions for probable/epidemiologically-linked cases were not significantly associated with seropositivity, unlike the American definition. • Public health outbreak control measures should use a low symptom threshold (particularly for generalized/systemic symptoms) for case exclusion and isolation when screening staff and residents in facility outbreaks A cross-sectional serological survey was carried out in two long term care facilities that experienced COVID-19 outbreaks in order to evaluate current clinical COVID-19 case definitions. Among individuals with a negative or no previous COVID-19 diagnostic test, myalgias, headache and loss of appetite were associated with serological reactivity. The US CDC probable case definition was also associated with seropositivity. Public health and infection control practitioners should consider these findings for case exclusion in outbreak settings. |
| Databáze: | OpenAIRE |
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