Decrease of vitamin D concentration in patients with HIV infection on a non nucleoside reverse transcriptase inhibitor-containing regimen
| Autor: | Rodrigo Moreno-Reyes, Eric Florence, Lutgarde Lynen, Joris Menten, Robert Colebunders, Anali Conesa-Botella |
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| Rok vydání: | 2010 |
| Předmět: |
lcsh:Immunologic diseases. Allergy
medicine.medical_specialty Efavirenz Nevirapine Virologie générale Gastroenterology vitamin D deficiency chemistry.chemical_compound Immune system Pharmacotherapy immune system diseases Internal medicine Virology Vitamin D and neurology Medicine Pharmacology (medical) business.industry Cholesterol Research Virologie médicale Biologie moléculaire virus diseases medicine.disease Regimen chemistry Immunology Molecular Medicine lcsh:RC581-607 business medicine.drug |
| Zdroj: | AIDS Research and Therapy AIDS Research and Therapy, 7 AIDS Research and Therapy, Vol 7, Iss 1, p 40 (2010) |
| ISSN: | 1742-6405 |
| Popis: | Background: Vitamin D is an important determinant of bone health and also plays a major role in the regulation of the immune system. Interestingly, vitamin D status before the start of highly active antiretroviral therapy (HAART) has been recently associated with HIV disease progression and overall mortality in HIV-positive pregnant women. We prospectively studied vitamin D status in HIV individuals on HAART in Belgium.We selected samples from HIV-positive adults starting HAART with a pre-HAART CD4 T-cell count >100 cells/mm 3 followed up for at least 12 months without a treatment change. We compared 25-hydroxyvitamin D plasma [25-(OH)D] concentration in paired samples before and after 12 months of HAART. 25-(OH)D levels are presented using two different cut-offs SCOPUS: ar.j info:eu-repo/semantics/published |
| Databáze: | OpenAIRE |
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