Perfusion MR Imaging in Gliomas: Comparison with Histologic Tumor Grade
| Autor: | Eun Ja Lee, Jae Hyoung Kim, Taemin Shin, Young Mee Kim, Gyung Kyu Lee, Kyeong Hun Kang, Jin Myung Jung, Sun Joo Lee, In Sung Park |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
Adult
Gadolinium DTPA Male medicine.medical_specialty Cerebral blood vessels flow dynamics Contrast Media Brain blood flow Astrocytoma Magnetic resonance (MR) contrast enhancement White matter Tumor grade Histologic grade Medicine Humans Radiology Nuclear Medicine and imaging neoplasms business.industry Brain Neoplasms Brain Mr imaging Magnetic Resonance Imaging nervous system diseases Cerebral blood volume medicine.anatomical_structure Cerebral blood flow Cerebrovascular Circulation Brain neoplasms MR Time curve Original Article Female Radiology business Glioblastoma Perfusion |
| Zdroj: | Korean Journal of Radiology |
| ISSN: | 2005-8330 1229-6929 |
| Popis: | OBJECTIVE To determine the usefulness of perfusion MR imaging in assessing the histologic grade of cerebral gliomas. MATERIALS AND METHODS In order to determine relative cerebral blood volume (rCBV), 22 patients with pathologically proven gliomas (9 glioblastomas, 9 anaplastic gliomas and 4 low-grade gliomas) underwent dynamic contrast-enhanced T2*-weighted and conventional T1- and T2-weighted imaging. rCBV maps were obtained by fitting a gamma-variate function to the contrast material concentration versus time curve. rCBV ratios between tumor and normal white matter (maximum rCBV of tumor / rCBV of contralateral white matter) were calculated and compared between glioblastomas, anaplastic gliomas and low-grade gliomas. RESULTS Mean rCBV ratios were 4.90 degrees +/- 1.01 for glioblastomas, 3.97 degrees +/- 0.56 for anaplastic gliomas and 1.75 degrees +/-1.51 for low-grade gliomas, and were thus significantly different; p |
| Databáze: | OpenAIRE |
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