Short‐Term Effects of Particle Size and Constituents on Blood Pressure in Healthy Young Adults in Guangzhou, China
| Autor: | Luke D. Knibbs, Xiao-Wen Zeng, Guang-Hui Dong, Zhi-Zhou He, Mika Komppula, Gongbo Chen, Pasi Jalava, Bo-Yi Yang, Marjut Roponen, Peng-Yue Guo, Li-Wen Hu, A. Leskinen, Bin Jalaludin |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male China Time Factors JAHA Spotlight on Air Pollution and Cardiovascular Disease air pollution Air pollution Blood Pressure 010501 environmental sciences medicine.disease_cause 01 natural sciences Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Environmental health medicine Humans panel study 030212 general & internal medicine Particle Size Young adult constituents Retrospective Studies Original Research 0105 earth and related environmental sciences particulate matter Air Pollutants business.industry Environmental Exposure Particulates Healthy Volunteers Term (time) Blood pressure Cardiovascular Diseases High Blood Pressure Female Particle size Morbidity Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| ISSN: | 2047-9980 |
| DOI: | 10.1161/jaha.120.019063 |
| Popis: | Background Although several studies have focused on the associations between particle size and constituents and blood pressure, results have been inconsistent. Methods and Results We conducted a panel study, between December 2017 and January 2018, in 88 healthy university students in Guangzhou, China. Weekly systolic blood pressure and diastolic blood pressure were measured for each participant for 5 consecutive weeks, resulting in a total of 440 visits. Mass concentrations of particles with an aerodynamic diameter of ≤2.5 µm (PM 2.5 ), ≤1.0 µm (PM 1.0 ), ≤0.5 µm (PM 0.5 ), ≤0.2 µm (PM 0.2 ), and number concentrations of airborne particulates of diameter ≤0.1 μm were measured. Linear mixed‐effect models were used to estimate the associations between blood pressure and particles and PM 2.5 constituents 0 to 48 hours before blood pressure measurement. PM of all the fractions in the 0.2‐ to 2.5‐μm range were positively associated with systolic blood pressure in the first 24 hours, with the percent changes of effect estimates ranging from 3.5% to 8.8% for an interquartile range increment of PM. PM 0.2 was also positively associated with diastolic blood pressure, with an increase of 5.9% (95% CI, 1.0%–11.0%) for an interquartile range increment (5.8 μg/m 3 ) at lag 0 to 24 hours. For PM 2.5 constituents, we found positive associations between chloride and diastolic blood pressure (1.7% [95% CI, 0.1%–3.3%]), and negative associations between vanadium and diastolic blood pressure (−1.6% [95% CI, −3.0% to −0.1%]). Conclusions Both particle size and constituent exposure are significantly associated with blood pressure in the first 24 hours following exposure in healthy Chinese adults. |
| Databáze: | OpenAIRE |
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