Acute nephrotic-range glomerular proteinuria following ibuprofen intoxication in two cats

Autor: Herrero, Yaiza, Iannucci, Claudia, Schreiber, Nora, Hansen, Bernard D, Vigani, Alessio
Přispěvatelé: University of Zurich, Vigani, Alessio
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: Case series summary In this report we describe the origin of protein loss and development of acute kidney injury after ibuprofen intoxication in two cats. Two 13-month-old neutered male domestic shorthair siblings were presented with acute kidney injury (AKI) and severe glomerular proteinuria following witnessed ibuprofen intoxication 3 days prior. Both cats presented with severe azotaemia (creatinine >900 µmol/l [>10 mg/dl]) and severe proteinuria (urine protein:creatinine [UPC] >20, normal Relevance and novel information This is the first clinical report of AKI with nephrotic-range protein losses following ibuprofen intoxication in cats. We propose that this finding is due to idiosyncratic glomerular injury, as described in humans.
Databáze: OpenAIRE