Chronic postsurgical pain in Europe: An observational study
| Autor: | Fletcher, Dominique, Stamer, Ulrike M., Pogatzki-Zahn, Esther, Zaslansky, Ruth, Tanase, Narcis Valentin, Perruchoud, Christophe, Kranke, Peter, Komann, Marcus, Lehman, Thomas, Lavand homme, P., Vercauteren, M., Meissner, W., Iohom, G., Cinnella, G., Aurilio, C., Belii, A., Filipescu, D., Rehberg-Klug, B., Decostered, I., Suter, M. R., Blumenthal, S., Puig, M., Garcia-Filoso, A., Brandner, B., Varvinskiy, A. M., Lisnyy, I., Kuchyn, I. |
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| Přispěvatelé: | Fletcher, Dominique, Stamer, Ulrike M., Pogatzki-Zahn, Esther, Zaslansky, Ruth, Tanase, Narcis Valentin, Perruchoud, Christophe, Kranke, Peter, Komann, Marcu, Lehman, Thoma, Lavand homme, P., Vercauteren, M., Meissner, W., Iohom, G., Cinnella, G., Aurilio, C., Belii, A., Filipescu, D., Rehberg-Klug, B., Decostered, I., Suter, M. R., Blumenthal, S., Puig, M., Garcia-Filoso, A., Brandner, B., Varvinskiy, A. M., Lisnyy, I., Kuchyn, I. |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Time Factor Risk Factors Surveys and Questionnaires Internal medicine Epidemiology medicine Clinical endpoint Humans Surveys and Questionnaire Prospective Studies Brief Pain Inventory 610 Medicine & health Prospective cohort study Multivariate Analysi Aged Pain Measurement Pain Postoperative business.industry Incidence (epidemiology) Incidence Risk Factor Chronic pain Middle Aged medicine.disease Europe Prospective Studie Anesthesiology and Pain Medicine Multivariate Analysis Neuropathic pain Orthopedic surgery Physical therapy Neuralgia Female Chronic Pain business Human |
| Popis: | BACKGROUND Chronic postsurgical pain (CPSP) is an important clinical problem. Prospective studies of the incidence, characteristics and risk factors of CPSP are needed. OBJECTIVES The objective of this study is to evaluate the incidence and risk factors of CPSP. DESIGN A multicentre, prospective, observational trial. SETTING Twenty-one hospitals in 11 European countries. PATIENTS Three thousand one hundred and twenty patients undergoing surgery and enrolled in the European registry PAIN OUT. MAIN OUTCOME MEASURES Pain-related outcome was evaluated on the first postoperative day (D1) using a standardised pain outcome questionnaire. Review at 6 and 12 months via e-mail or telephonic interview used the Brief Pain Inventory (BPI) and the DN4 (Douleur Neuropathique four questions). Primary endpoint was the incidence of moderate to severe CPSP (numeric rating scale, NRS ≥3/10) at 12 months. RESULTS For 1044 and 889 patients, complete data were available at 6 and 12 months. At 12 months, the incidence of moderate to severe CPSP was 11.8% (95% CI 9.7 to 13.9) and of severe pain (NRS ≥6) 2.2% (95% CI 1.2 to 3.3). Signs of neuropathic pain were recorded in 35.4% (95% CI 23.9 to 48.3) and 57.1% (95% CI 30.7 to 83.4) of patients with moderate and severe CPSP, respectively. Functional impairment (BPI) at 6 and 12 months increased with the severity of CPSP (P |
| Databáze: | OpenAIRE |
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