Functional imbalance of visual pathways indicates alternative face processing strategies in autism
| Autor: | Heinrich Lanfermann, Sabine Feineis-Matthews, D. Hubl, Andrea Federspiel, Werner Strik, Sven Bölte, Fritz Poustka, Thomas Dierks |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Adolescent genetic structures Emotions Superior parietal lobule Visual system Visual processing medicine Humans Visual Pathways Autistic Disorder Visual search Analysis of Variance Behavior Brain Mapping Fusiform gyrus Brain Medial frontal gyrus Frontal eye fields medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Pattern Recognition Visual Face Autism Neurology (clinical) Psychology Neuroscience Photic Stimulation |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1526-632X 0028-3878 |
| Popis: | Objective: To investigate whether autistic subjects show a different pattern of neural activity than healthy individuals during processing of faces and complex patterns. Methods: Blood oxygen level–dependent (BOLD) signal changes accompanying visual processing of faces and complex patterns were analyzed in an autistic group (n = 7; 25.3 [6.9] years) and a control group (n = 7; 27.7 [7.8] years). Results: Compared with unaffected subjects, autistic subjects demonstrated lower BOLD signals in the fusiform gyrus, most prominently during face processing, and higher signals in the more object-related medial occipital gyrus. Further signal increases in autistic subjects vs controls were found in regions highly important for visual search: the superior parietal lobule and the medial frontal gyrus, where the frontal eye fields are located. Conclusions: The cortical activation pattern during face processing indicates deficits in the face-specific regions, with higher activations in regions involved in visual search. These findings reflect different strategies for visual processing, supporting models that propose a predisposition to local rather than global modes of information processing in autism. |
| Databáze: | OpenAIRE |
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