Low Agreement Between Initial and Revised European Consensus on Definition and Diagnosis of Sarcopenia Applied to People Living With HIV
| Autor: | Claudio M. Alves Junior, Rafael Deminice, José David G. Cárdenas, Noemy F. Castro, Camila S. Padilha, Kristine M. Erlandson, Vitor H F Oliveira, Poliana Camila Marinello, Ana L. Borsari, Allison R. Webel |
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| Přispěvatelé: | Universidade Estadual de Londrina (UEL), Case Western Reserve Univ, Salgado Inst Integral Hlth, Universidade Estadual Paulista (Unesp), Univ Colorado |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Sarcopenia Human immunodeficiency virus (HIV) HIV Infections medicine.disease_cause physical examination Low muscle mass Primary outcome medicine Humans Pharmacology (medical) muscle strength dynamometer muscle weakness body composition business.industry muscle function neuromuscular disease Middle Aged musculoskeletal system medicine.disease Gait speed body regions Europe Infectious Diseases Cross-Sectional Studies Physical therapy Muscle strength Female business Older people human activities Kappa |
| Zdroj: | Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 1944-7884 |
| Popis: | Made available in DSpace on 2021-06-25T12:17:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01 Brazilian grants from SETI (Secretaria da Ciencia, Tecnologia e Ensino Superior do Parana) Ministry of Education Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Brazilian scholarship for a research internship at A.R.W.'s laboratory in Cleveland, USA Background: In 2019, the European Working Group on Sarcopenia in Older People (EWGSOP2) proposed low muscle strength as the primary outcome for sarcopenia diagnosis instead of low muscle mass, as proposed in 2010 (EWGSOP1). Therefore, the aim of this study was to compare the prevalence of sarcopenia using both EWGSOP1 and EWGSOP2 operational definitions in people living with HIV (PLHIV) and to determine the agreement and correlation between different tests proposed by EWGSOP2. Setting: Cross-sectional study, where 302 PLHIV (151 men), 51.7 +/- 9.0 years old were evaluated for the presence of sarcopenia using both EWGSOP1 and EWGSOP2 operational definitions. Methods: Appendicular skeletal muscle was estimated using bioimpedance analysis. Handgrip strength, chair stand, gait speed, and static balance were used as muscle function measures. Agreement was determined using Cohen kappa and Pearson correlation coefficient was calculated. Results: Sarcopenia prevalence was 4.3% using EWGSOP1 and 1.0% using EWGSOP2. Agreement for sarcopenia diagnosis between EWGSOP1 and EWGSOP2 was fair (k = 0.37, P < 0.01). From the 13 cases of sarcopenia diagnosed using EWGSOP1, only 3 cases (23.1%) were also diagnosed using EWGSOP2. A medium correlation (r = -0.32, P < 0.01) and poor agreement (k = 0.14, P < 0.01) between muscle strength tests (handgrip strength and chair stand) were observed. Concordance between handgrip and chair stand was observed in 11 participants only, whereas 65 participants were considered to have low muscle strength using chair stand but not using handgrip. Conclusions: Lower sarcopenia prevalence using EWGSOP2 and low agreement between EWGSOP1 and EWGSOP2 operational definitions in diagnosing sarcopenia were observed in PLHIV. Univ Estadual Londrina, Dept Phys Educ, Londrina, Parana, Brazil Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Res Campus,10900 Euclid Ave, Cleveland, OH 44106 USA Univ Estadual Londrina, Hlth Sci Ctr, Londrina, Parana, Brazil Salgado Inst Integral Hlth, Londrina, Parana, Brazil Univ Estadual Londrina, Biol Sci Ctr, Londrina, Parana, Brazil State Univ Sao Paulo, Dept Phys Educ, Presidente Pmdente, SP, Brazil Univ Colorado, Anschutz Med Campus, Aurora, CO USA State Univ Sao Paulo, Dept Phys Educ, Presidente Pmdente, SP, Brazil CAPES: 88881.132132/2016-01 |
| Databáze: | OpenAIRE |
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