Cottonseed (gossypol) intake during gestation and lactation does affect the ovarian population in ewes and lambs?
Autor: | Tsai Mui Siu, Helder Louvandini, Tairon Pannunzio da Silva, Patrícia Spoto Corrêa, Carolina Rodriguez Jimenez, Ricardo Lopes Dias da Costa, Débora Botéquio Moretti |
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Rok vydání: | 2021 |
Předmět: |
endocrine system
040301 veterinary sciences Offspring Population Ice calving Biology 0403 veterinary science Cottonseed Andrology 03 medical and health sciences chemistry.chemical_compound Pregnancy Lactation Follicular phase medicine Animals education Progesterone 030304 developmental biology 0303 health sciences education.field_of_study Sheep General Veterinary Reproduction Ovary Gossypol 04 agricultural and veterinary sciences medicine.anatomical_structure chemistry Oocytes Female Corpus luteum |
Zdroj: | Research in Veterinary Science. 135:557-567 |
ISSN: | 0034-5288 |
Popis: | The aim of this study was to evaluate if the cottonseed intake during gestation and lactation affects the ovarian population in ewes and lambs. Therefore, 39 ewes were evaluated during 10 months under two treatments: Cottonseed and soybeans. The quantification of ovarian follicular dynamics was analyzed by ultrasound and the determination of progesterone and estradiol levels was interpreted by radioimmunoassay. After weaning, ovaries of lambs (n = 10) were collected by ovariectomy and fixed for the assessment of follicular parameters as normality, classification, diameter, ultrastructure, stereology, and as well as immunoexpression of the α-estradiol receptor α (ER-α). The results showed that the cottonseed consumption altered neither the ovarian nor the hormonal follicular dynamics of Santa Ines ewes after calving and did not affect the normality, classification, diameter, stereology and follicular ultrastructure of offspring. Nevertheless, the offspring of ewes fed with cottonseed showed high ER-α immunoexpression in the ovarian structures. It is concluded that cottonseed did not affect the maternal-descendant follicular dynamics. However, lambs' ovaries had highest α-ER immunoexpression in oocytes, granulosa and theca cells and corpus luteum. This fact warns of a possible change in the future steroidogenic response of these lambs that had progenitors consuming cottonseed in their reproductive period. |
Databáze: | OpenAIRE |
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