Cardiolipin from beef heart mitochondria: Fatty acid positioning and molecular species distribution
| Autor: | Y.C. Awasthi, Frederick L. Crane, T.W. Keenan |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Silver
Linoleic acid Biophysics Acetates Biology Biochemistry Glycerides chemistry.chemical_compound Ethanolamine Cardiolipin Animals Choline Diglyceride Molecular Biology Phospholipids chemistry.chemical_classification Chromatography Beef heart mitochondria Myocardium Phosphatidylethanolamines Fatty Acids Fatty acid Cell Biology Mitochondria Muscle Linoleic Acids chemistry Phosphatidylcholines Cattle lipids (amino acids peptides and proteins) Chromatography Thin Layer Polyunsaturated fatty acid |
| Zdroj: | Biochemical and Biophysical Research Communications. 40:1102-1109 |
| ISSN: | 0006-291X |
| DOI: | 10.1016/0006-291x(70)90908-3 |
| Popis: | The positioning of fatty acids within cardiolipin from beef heart mitochondria was determined and compared to phosphatidyl choline and phosphatidyl ethanolamine; from the same source. Unsaturated fatty acids were preferentially esterified in the β-position and saturated fatty acids were contained preferentially in the α-position of the choline and ethanolamine phosphatides. In contrast, fatty adds were nearly randomly distributed between the (α- and β-positions of cardiolipin. On acetolysis, cardiolipin yielded diglyceride acetates which were separated into three distinct species, trienes, tetraenes and pentaenees, by argentation thin-layer chromatography. Tetraenes accounted for more than 75% of the total diglyceride acetates and contained 94% linoleic acid, suggesting the existence of a molecular species of cardiolipin containing solely linoleic acid. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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