Performance of diagnostic ultrasound to identify causes of hydramnios
| Autor: | Gwenaelle Le Bouar, Marie-José Adam, Anne-Sophie Cabaret-Dufour, Laurence Contin, Cécile Tardif, Isabelle Enderle, Alexis Arnaud, Maïa Proisy, Sylvie Jaillard, Maela Le Lous, Laurent Pasquier |
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| Přispěvatelé: | Service de Gynécologie et Obstétrique [Rennes] = Gynaecology [Rennes], CHU Pontchaillou [Rennes], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de chirurgie pédiatrique [Rennes] = Paediatric / Pediatric surgery [Rennes], Département de Radiologie [CHU de Rennes], Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Service de cytogénétique [Rennes], Service de génétique [Rennes], Jonchère, Laurent, Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UR) |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Polyhydramnios medicine.medical_specialty [SDV]Life Sciences [q-bio] Pregnancy in Diabetics [SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics Bartter syndrome Myotonic dystrophy Ultrasonography Prenatal 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Diabetes mellitus medicine Humans Medical diagnosis Genetics (clinical) Retrospective Studies 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics and Gynecology Retrospective cohort study medicine.disease 3. Good health [SDV] Life Sciences [q-bio] Diabetes Gestational [SDV.MHEP.GEO] Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics Atresia Amniocentesis Etiology Female Radiology business |
| Zdroj: | Prenatal Diagnosis Prenatal Diagnosis, Wiley, 2021, 41 (1), pp.111-122. ⟨10.1002/pd.5825⟩ Prenatal Diagnosis, 2021, 41 (1), pp.111-122. ⟨10.1002/pd.5825⟩ |
| ISSN: | 1097-0223 0197-3851 |
| Popis: | International audience; Introduction: We aimed to assess the diagnostic yield of ultrasonography in the identification of the etiology of hydramnios, and the added value of MRI or amniocentesis.Methods: We conducted a single-center retrospective study including pregnancies with confirmed hydramnios (defined as deepest pocket ≥8 cm) between January 2013 and May 2017. Twin pregnancies, secondary hydramnios discovered after the diagnosis of a causal pathology, and pregnancies of unknown outcome were excluded. All pregnancies underwent a targeted scan, and selected cases underwent MRI or amniocentesis.Results: A total of 158 patients with confirmed hydramnios were included. Hydramnios was associated with a fetal pathology in 37 cases (23.4%), with diabetes in 39 (24.6%), isolated macrosomia in 16 (10.1%), and considered idiopathic in 66 (41.7%). Ultrasonography established a diagnosis of the underlying pathology in 73% of cases. Amniocentesis was done in 31 cases (20%) and it allowed diagnosis of chromosome anomalies, esophageal atresia, myotonic dystrophy congenital type, Prader-Willi syndrome, and Bartter syndrome. MRI was done in 15 cases (10%) and it allowed one additional diagnosis of esophageal atresia. The diagnostic yields of MRI and amniocentesis were 91.7% and 95.2%, respectively. There were 5 false positive diagnoses at ultrasonography, and 1 false positive diagnosis at MRI.Conclusion: Hydramnios can be associated with a wide variety of underlying pathologies. Diagnostic ultrasound can attain a diagnosis in the majority of cases. Amniocentesis offers a valuable complementary assessment. |
| Databáze: | OpenAIRE |
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