Adductor Spasmodic Dysphonia Improves with Bilateral Thalamic Deep Brain Stimulation: Report of 3 Cases Done Asleep and Review of Literature
| Autor: | Virgilio Gerald H. Evidente, Robin Garrett, Maris H. Evidente, Margaret Lambert, David G. Lott, Manikandan Sugumaran, Francisco A. Ponce |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Deep brain stimulation medicine.medical_treatment Deep Brain Stimulation Essential Tremor DBS Spasmodic dysphonia Audiology behavioral disciplines and activities laryngeal dystonia Voice tremor Thalamus thalamic DBS medicine Humans Wakefulness Laryngeal dystonia Aged Ventral Thalamic Nuclei Essential tremor business.industry Brief Report Speech Intelligibility medicine.disease Dysphonia nervous system diseases Adductor spasmodic dysphonia surgical procedures operative Female Facial grimacing medicine.symptom business |
| Zdroj: | Tremor and Other Hyperkinetic Movements |
| ISSN: | 2160-8288 |
| Popis: | Background: To date, there are only six published reports of adductor spasmodic dysphonia (SD) responding to awake thalamic deep brain stimulation (DBS). Methods: We retrospectively reviewed cases of Essential Tremor (ET) with SD that were seen in our center from 2012 to 2020. We further identified those that have undergone thalamic DBS, and had a blinded laryngologist rate first the audio voice recordings before and after DBS using the Unified Spasmodic Dysphonia Rating Scale (USDRS), and the video recordings last to rate the related movements and facial grimacing. Results: We identified three cases of adductor SD with ET that had undergone bilateral ventralis intermedius (VIM) DBS under general anesthesia. All patients noted improvement of their limb and voice tremor, as well as their SD post-DBS. Although improvement of tremor was observed even with initial programming in all three, improvement of SD was noted only upon reaching higher amplitudes or wider pulse widths. Blinded voice assessments showed improvement of USDRS scores post-DBS compared to pre-DBS, and with stimulator on compared to stimulator off. Discussion: We report the first three cases of SD responding favorably to bilateral VIM asleep DBS and summarize the nine cases so far of SD who have undergone thalamic DBS. |
| Databáze: | OpenAIRE |
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