Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients
| Autor: | Axel Haglund, Mikael Landén, Alina Karanti, Dag Tidemalm, Bo S. Runeson |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Bipolar Disorder Epidemiology Science Poison control Suicide Attempted Suicide prevention Cohort Studies Sex Factors Risk Factors mental disorders Mental Health and Psychiatry medicine Odds Ratio Medicine and Health Sciences Humans Public and Occupational Health Bipolar disorder Registries Psychiatry Depression (differential diagnoses) Sweden Multidisciplinary business.industry Mood Disorders Odds ratio medicine.disease Mood disorders Cohort Medicine Female sense organs business Cohort study Follow-Up Studies Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 4, p e94097 (2014) |
| ISSN: | 1932-6203 |
| Popis: | ObjectiveBipolar disorder is associated with high risk of self-harm and suicide. We wanted to investigate risk factors for attempted suicide in bipolar patients.MethodThis was a cohort study of 6086 bipolar patients (60% women) registered in the Swedish National Quality Register for Bipolar Disorder 2004-2011 and followed-up annually 2005-2012. Logistic regression was used to calculate adjusted odds ratios for fatal or non-fatal attempted suicide during follow-up.ResultsRecent affective episodes predicted attempted suicide during follow-up (men: odds ratio = 3.63, 95% CI = 1.76-7.51; women: odds ratio = 2.81, 95% CI = 1.78-4.44), as did previous suicide attempts (men: odds ratio = 3.93, 95% CI = 2.48-6.24; women: odds ratio = 4.24, 95% CI = 3.06-5.88) and recent psychiatric inpatient care (men: odds ratio = 3.57, 95% CI = 1.59-8,01; women: odds ratio = 2.68, 95% CI = 1.60-4.50). Further, those with many lifetime depressive episodes were more likely to attempt suicide. Comorbid substance use disorder was a predictor in men; many lifetime mixed episodes, early onset of mental disorder, personality disorder, and social problems related to the primary group were predictors in women.ConclusionThe principal clinical implication of the present study is to pay attention to the risk of suicidal behaviour in bipolar patients with depressive features and more severe or unstable forms of the disorder. |
| Databáze: | OpenAIRE |
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