Interobserver and Test-Retest Reproducibility of T1ρ and T2 Measurements of Lumbar Intervertebral Discs by 3T Magnetic Resonance Imaging
| Autor: | Sungjun Kim, Yeon Hwa Yoo, Hanna Yoo, Moon Jung Hwang, Tae Sub Chung, Robert D. Peters, Jin Suck Suh, Young Han Lee, Na Lae Eun, Choon Sik Yoon |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Nucleus Pulposus Intraclass correlation T2 mapping Intervertebral Disc Degeneration Disc degeneration Severity of Illness Index T1 rho 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Lumbar Region of interest Statistical significance medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Aged Reproducibility Lumbar Vertebrae medicine.diagnostic_test business.industry Musculoskeletal Imaging Reproducibility of Results Intervertebral disc Magnetic resonance imaging Middle Aged Magnetic Resonance Imaging medicine.anatomical_structure Female Original Article Nuclear medicine business 030217 neurology & neurosurgery |
| Zdroj: | Korean Journal of Radiology |
| ISSN: | 2005-8330 |
| Popis: | OBJECTIVE To investigate the interobserver and test-retest reproducibility of T1ρ and T2 measurements of lumbar intervertebral discs using 3T magnetic resonance imaging (MRI). MATERIALS AND METHODS This study included a total of 51 volunteers (female, 26; male, 25; mean age, 54 ± 16.3 years) who underwent lumbar spine MRI with a 3.0 T scanner. Amongst these subjects, 40 underwent repeat T1ρ and T2 measurement acquisitions with identical image protocol. Two observers independently performed the region of interest measurements in the nuclei pulposi of the discs from L1-2 through L5-S1 levels. Statistical analysis was performed using intraclass correlation coefficient (ICC) with a two-way random model of absolute agreement. Comparison of the ICC values was done after acquisition of ICC values using Z test. Statistical significance was defined as p value < 0.05. RESULTS The ICCs of interobserver reproducibility were 0.951 and 0.672 for T1ρ and T2 mapping, respectively. The ICCs of test-retest reproducibility (40 subjects) for T1ρ and T2 measurements were 0.922 and 0.617 for observer A and 0.914 and 0.628 for observer B, respectively. In the comparison of the aforementioned ICCs, ICCs of interobserver and test-retest reproducibility for T1ρ mapping were significantly higher than T2 mapping (p < 0.001). CONCLUSION The interobserver and test-retest reproducibility of T1ρ mapping were significantly higher than those of T2 mapping for the quantitative assessment of nuclei pulposi of lumbar intervertebral discs. |
| Databáze: | OpenAIRE |
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