Salmon gill poxvirus disease in Atlantic salmon fry as recognized by improved immunohistochemistry also demonstrates infected cells in non-respiratory epithelial cells
| Autor: | P E Petersen, D H Christensen, B Saure, Ole Bendik Dale, F Manji, C Skjengen, Mona Cecilie Gjessing, Saima Mohammad, S.C. Weli |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Gills
0301 basic medicine endocrine system animal structures Denmark Veterinary (miscellaneous) Salmo salar Poxviridae Infections Disease Aquatic Science Biology Microbiology Fish Diseases 03 medical and health sciences Animals Respiratory system Mouth Norway Poxviridae fungi Epithelial Cells Common denominator 030104 developmental biology Scotland Apoptosis Respiratory epithelium Immunohistochemistry Hemophagocytosis Salmon gill poxvirus |
| Zdroj: | Journal of Fish Diseases. 41:1103-1110 |
| ISSN: | 0140-7775 |
| DOI: | 10.1111/jfd.12802 |
| Popis: | Gill diseases cause serious losses in farming of Atlantic salmon and the number of agents involved increases. Salmon gill poxvirus (SGPV) and the gill disease in causes where SGPV apparently was the only disease-causing agent were initially characterized. Recently, it was further shown that SGPV can be a common denominator in widely different multifactorial gill diseases. Here, we present the challenge of diagnosing gill disease with SGPV in salmon fry of 0,3-5 grams. Apoptosis of gill lamellar epithelial cells and hemophagocytosis was also observed in fry similar to findings in smolts and grow-out fish. Using our newly developed immunohistochemistry method, we further demonstrate that some of the apoptotic epithelial cells covering the oral cavity were positive for SGPV. Thus, SGPV is not restricted to respiratory epithelium alone and may infect the fish at very early life stages. Furthermore, as the cases examined here are from Norway, Faroe Island and Scotland, we show that SGPV is more widespread than previously reported. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text