Quantitative image analysis of vertebral body architecture—improved diagnosis in osteoporosis based on high-resolution computed tomography
| Autor: | A Mundinger, B Wiesmeier, E Dinkel, A Helwig, A Beck, J Schulte Moenting |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
medicine.medical_specialty High-resolution computed tomography Adolescent Bone density Osteoporosis Lumbar Bone Density medicine Humans Radiology Nuclear Medicine and imaging In patient Quantitative computed tomography Osteoporosis Postmenopausal Aged Lumbar Vertebrae medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Vertebral body Regression Analysis Bone mineral content Female Radiology Tomography X-Ray Computed business |
| Zdroj: | The British Journal of Radiology. 66:209-213 |
| ISSN: | 1748-880X 0007-1285 |
| DOI: | 10.1259/0007-1285-66-783-209 |
| Popis: | 71 women, 64 post-menopausal, were examined by single-energy quantitative computed tomography (SEQCT) and by high-resolution computed tomography (HRCT) scans through the middle of lumbar vertebral bodies. Computer-assisted image analysis of the high-resolution images assessed trabecular morphometry of the vertebral spongiosa texture. Texture parameters differed in women with and without age-reduced bone density, and in the former group also in patients with and without vertebral fractures. Discriminating parameters were the total number, diameter and variance of trabecular and intertrabecular spaces as well as the trabecular surface (p0.05)). A texture index based on these statistically selected morphometric parameters identified a subgroup of patients suffering from fractures due to abnormal spongiosal architecture but with a bone mineral content not indicative for increased fracture risk. The combination of osteodensitometric and trabecular morphometry improves the diagnosis of osteoporosis and may contribute to the prediction of individual fracture risk. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|