Sensory stimulation in acute stroke therapy

Autor: Daniel von Bornstädt, Nielsen Lagumersindez Denis, Matthias Endres, Pierre Seners, Karen Gertz, Jean-Claude Baron
Rok vydání: 2018
Předmět:
Zdroj: Journal of Cerebral Blood Flow & Metabolism. 38:1682-1689
ISSN: 1559-7016
0271-678X
Popis: The beneficial effects of cortical activation for functional recovery after ischemic stroke have been well described. However, little is known about the role of early sensory stimulation, i.e. stimulation during first 6 h after stroke onset even during acute treatment. In recent years, various preclinical studies reported significant effects of acute sensory stimulation that range from entire neuroprotection to increased infarct volumes by 30–50%. Systematic knowledge about the effect of acute sensory stimulation on stroke outcome is highly relevant as stroke patients are subject to uncontrolled sensory stimulation during transport, acute treatment, and critical care. This article discusses the current stage of knowledge about acute sensory stimulation and provides directions for future experimental and clinical trials.
Databáze: OpenAIRE