Variation of C-Reactive Protein and White Blood Cell Counts in Spinal Operation: Primary Fusion Surgery Versus Revision Fusion Surgery
| Autor: | Kyung Tag Kang, Dong Wuk Son, Su Hun Lee, Soon Ki Sung, Geun Seong Song, Sang Weon Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Reoperation
medicine.medical_specialty Spinal fusion surgery Surgical wound infection Spinal operation C-reactive protein 03 medical and health sciences 0302 clinical medicine Lumbar White blood cell medicine 030222 orthopedics Fusion surgery Clinical Article biology business.industry medicine.disease Comorbidity Surgery medicine.anatomical_structure Anesthesia biology.protein Neurosurgery business 030217 neurology & neurosurgery |
| Zdroj: | Korean Journal of Spine |
| ISSN: | 2093-6729 1738-2262 |
| Popis: | Objective Serum C-reactive protein (CRP) concentrations and white blood cell (WBC) count are commonly used to identify postoperative wound infections. We investigated whether changes in serum CRP levels and WBC counts actually differed between patients undergoing revision spinal fusion surgery and those undergoing a primary fusion. Methods Patients who underwent posterolateral fusion (PLF) surgery at Pusan National University Yangsan Hospital between October 2013 and April 2015 were considered for this study. Sixty-seven patients with primary lumbar PLF (pPLF) and 21 with revision PLF (rPLF) were enrolled. A retrospective assessment of preoperative and postoperative CRP levels and WBC count was undertaken. Also, we gathered peak CRP day, and CRP normalization days. Comorbidity data were also obtained to evaluate any effects on the course of CRP and WBC count postoperatively. Results CRP levels peaked at 3 days after surgery. The maximum CRP values recorded for each group: 4.17 (standard deviation [SD], 4.18) mg/dL and 4.88 (SD, 3.03) mg/dL for pPLF and rPLF. This difference was not statistically significant (p=0.24). A rapid fall in CRP within 5-9 days was observed for both groups. Conclusion Out of our expectation, changes in CRP levels after spinal fusion surgery follow the same course regardless of whether it is a revision operation or not. Because of this result, both the primary PLF surgery and revision PLF surgery should be monitored using CRP in the similar way and the antibiotic administration should be determined. |
| Databáze: | OpenAIRE |
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